Ospemifene

Ospemifene menopause ke baad andaam nihani ki khushki aur jinsi taalluq ke dauran takleef ki aik goli hai. Yeh dawaon ke us giroh se hai jise SERMs kehte hain, yani selective estrogen receptor modulators.

Pakistan Menopause Society ki sifarishaat batati hain ke SERMs jism ke kuch hisson mein estrogen jaisa kaam karti hain aur kuch mein ise rokti hain (section 5.7). Is liye yeh aam maanon mein HRT nahin, halanke yeh jism mein estrogen ke receptors ke zariye hi kaam karti hai.

Jin alamaat ke liye yeh hai, un ka aik tibbi naam hai: genitourinary syndrome of menopause, ya GSM. NICE NG23 andaam nihani aur farj (zanana sharam gaah) ki khushki, jinsi taalluq ke dauran takleef, farj aur andaam nihani mein be aaraami ya jalan, aur peshaab karte hue be aaraami ya dard ko genitourinary symptoms mein ginta hai.

Menopause ke aas paas jab estrogen kam hota hai to andaam nihani aur farj ki jild patli aur khushk ho sakti hai. PMS ki sifarishaat ise genitourinary syndrome of menopause kehti hain, woh naam jis ne vulvovaginal atrophy, yani andaam nihani aur farj ki jild ka patla ho jana, ki jagah li (1.5.2), aur ise menopause ke baad ke pehle chand saalon mein rakhti hain (Table 1). NICE NG23 is khushki ko masane ki un tabdeeliyon ke saath ginta hai jo is ke saath aa sakti hain.

NICE NG23 genitourinary symptoms ke liye aik tarteeb batata hai. Jin auraton ko kabhi chhaati ka cancer nahin hua, un ke liye pehla qadam usi jagah lagane wala estrogen hai, aur baghair hormone wale moisturiser aur lubricant is ke saath ya is ki jagah. Agar in se farq na pare to agla qadam andaam nihani mein lagane wala prasterone hai. Ospemifene munh se khane wala raasta hai, tab ke liye jab usi jagah lagane wali koi bhi cheez amali taur par mushkil ho (1.5.11). NICE misaal ke taur par mazoori ka naam leta hai.

British Menopause Society aik qadam aage jati hai. Woh ospemifene ko un auraton ke liye munasib intikhab samajhti hai jo usi jagah lagane wala estrogen istemal nahin kar saktin, ya jo andaam nihani ke andar koi bhi ilaaj lagane ke bajaye goli lena chahti hain.

Donon mein se koi bhi hidayat ospemifene ka naam hot flush, raat ke paseenon ya mood ke liye nahin letin. Yeh alamaat ke aik giroh ka ilaaj hai.

Yeh har aik ke liye nahin. European Menopause and Andropause Society (EMAS) kehti hai ke jin auraton ko is waqt khoon ka lothra ho ya pehle kabhi hua ho, woh ise istemal na karein, aur British Menopause Society lothron aur faalij ke baare mein ehtiyaat ka kehti hai. Yeh aap ke liye theek hai ya nahin, yeh aap ki sehat ki kahani par munhasir hai, aur yeh baat us doctor se karne ki hai jo ise likhe ga.

Agar khushki, jalan ya jinsi taalluq ke dauran takleef kai hafton se chal rahi hai to appointment lena banta hai. Yeh aik tibbi alamat hai jis ke tibbi ilaaj maujood hain, aur ise bardasht karte rehna zaroori nahin.

Agar jinsi taalluq ke baad, ya mahwari band ho jane ke baad, khoon aaye to jald doctor ko dikhayen. Pakistan Menopause Society jinsi taalluq ke baad aur menopause ke baad khoon aane ko un khatre ki alamaat mein ginti hai jin ki jaanch zaroori hai (section 2.3), chahe aap koi bhi ilaaj le rahi hon.

Agar yeh baat karna naamumkin lagta hai to aap akeli nahin. PMS ki sifarishaat likhti hain ke ho sakta hai bohat si Pakistani auratein jinsi ya peshaab ki alamaat ka zikr tab tak na karein jab tak un se izzat se aur akele mein na poocha jaye (section 2.2). Alamat kaghaz par likh kar doctor ko de dena aik raasta hai. Yeh poochna ke kya koi lady doctor mil sakti hai, doosra.

Kuch auraton ke liye andaam nihani mein lagane wale ilaaj ki mushkil jismani hoti hi nahin. Mushkil hoti hai mushtarka ghar mein privacy ki, ya kuch chhoone ya andar rakhne ki be aaraami ki, ya paaki aur namaz ke un sawalon ki jo unhon ne kabhi kisi se pooche hi nahin. Yeh asal wajhein hain, aur British Menopause Society bas goli ko tarjeeh dene ko bhi ospemifene par ghaur karne ki wajhon mein ginti hai.

Namaz, wuzu ya roze ke sawal kisi mustanad aalim se poochne ke hain. Ramzan mein goli kab leni hai, yeh sawal us doctor se poochne ka hai jo ise likhta hai.